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Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.

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合作者:
信息的提供 (责任方):
heba samir,Cairo University
October 1, 2018
October 4, 2018
October 5, 2018
October 2018
July 2019   (主要结果测量的最终数据收集日期)
root coverage[ Time Frame: 9 months ]
measured in millimeter

与当前相同
  • Gingival esthetics[ Time Frame: 9 months ]
    Root coverage esthetic score
  • Recession width[ Time Frame: 9 months ]
    measured in millimeter
  • Clinical attachment level[ Time Frame: 9 months ]
    measured in millimeter
  • Width of keratinized gingiva[ Time Frame: 9 months ]
    measured in millimeter
  • Probing depth[ Time Frame: 9 months ]
    measured in millimeter
  • Gingival thickness[ Time Frame: 9 months ]
    measured in millimeter
  • Post-operative pain[ Time Frame: measured daily for the first 2 weeks post- operatively. ]
    Visual analog scale (VAS) Questionnaire
  • Patient Satisfaction[ Time Frame: 9 months ]
    Post-Surgical Patient Satisfaction Questionnaire
  • Early wound healing[ Time Frame: 1,2,4 weeks post- surgical ]
    Early wound healing index
 
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
Root Coverage After the Use of Coronally Advanced Flap With Advanced Platelet Rich Fibrin (A- PRF) Compared With Subepithelial Connective Tissue Graft in Management of Miller Class I and II Gingival Recession. A Randomized Clinical Trial

patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results. Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.

- Population (P): Patients with single Miller class I, II gingival recessions. - Intervention (I): Coronally advanced flap (CAF) plus platelet rich fibrin (A-PRF). - Comparator (C): Coronally advanced flap (CAF) plus subepithelial connective tissue graft (SCTG). - Primary Outcome (O): Root coverage (mm). - Time frame: 9 months. - Study design: Randomized controlled clinical trial. - Patients are to be selected from the outpatient clinic of the department of Oral Medicine and Periodontology-Cairo University
Interventional
N/A
分配: Randomized
干预模型: Parallel Assignment
干预模型描述:
盲法: Interventional
盲法描述:
主要目的: Treatment
  • Procedure: CAF + (A-PRF)
    advanced platelet rich fibrin prepared by low speed centrfugation concept(LSCC) together with coronally advanced flap .
  • Procedure: CAF+SCTG
    cornally advanced flap plus subepithilial connective tissue graft harvested from the palate
  • Active Comparator: intervention
    CAF+ APRF
  • Active Comparator: control
    CAF+SCTG
 
Not yet recruiting
20
与当前相同
October 2019
July 2019   (主要结果测量的最终数据收集日期)
Inclusion Criteria: - Systemically healthy patients 18 years old and older both males and females. - Good oral hygiene after phase I therapy. - Miller's class I or II gingival recession. - Not using antibiotics, steroids, chemotherapy or other medications that may modify results of the surgery and healing. - Cooperative patients able and accept to come for follow up appointments Exclusion Criteria: - Pregnant or lactating females. - Current Smokers. - Patients with any systemic disease that may affect the periodontal healing. - Teeth with endodontic treatment, buccal restoration or caries. - Patients with poor oral hygiene
参与研究的性别: All
最小年龄:15 Years ,最大年龄:N/A  
没有
 
Yes
研究美国FDA监管的药品: No
研究涉及美国FDA监管的设备产品: No
计划分享 IPD:
heba samir,Cairo University
Cairo University
Study Chair: manal M hosny, professor faculty of Dentistry-Cairo University
Study Director: engi A mahmoud, assistant professor faculty of Dentistry-Cairo University
Cairo University
October 2018

ICMJE     国际医学期刊编辑委员会和 世界卫生组织 ICTRP 要求的元素
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