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Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR

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合作者:
信息的提供 (责任方):
Sarah AbdAllah Mohamed,Cairo University
October 4, 2018
October 5, 2018
October 5, 2018
October 20, 2018
September 20, 2019   (主要结果测量的最终数据收集日期)
Horizontal bone gain[ Time Frame: 6 months ]
The amount of horizontal bone gain will be measured by cone beam computed tomography

与当前相同
  • [ Time Frame: ]
 
Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR
Ridge Augmentation Using Autologous Concentrated Growth Factors (CGF) Enriched Bone Graft Matrix (Sticky Bone) Versus Guided Bone Regeneration Using Native Collagen Membrane in Horizontally Deficient Maxilla

Guided bone regeneration (GBR) using bone graft and barrier membrane is a well-established technique for augmentation of atrophic alveolar ridges. There are many techniques for ridge augmentation involves the use of bone grafting materials, barrier membranes, possibly some tenting/fixation screws the stability of bone graft, space maintenance, angiogenesis, and tension free primary suture are essential for success.

Common techniques introduced for horizontal ridge augmentation are Guided Bone Regeneration (GBR), there are many techniques for ridge augmentation involves the use of bone grafting materials, barrier membranes, possibly some tenting/fixation screws. For successful GBR, stability of bone graft, space maintenance, angiogenesis, and tension free primary suture are essential. Space maintenance with particulate bone graft should be provided during healing period. However particulate bone graft is easily migrated when grafted on the large horizontal bone defect. To reconstruct large bony defect or for the 3-dimensional ridge augmentation, bone tack on the collagen membrane or titanium mesh is required to contain particulate bone graft during healing but these procedures are surgically time consuming and technique sensitive. Sticky bone is biologically solidified bone graft which is entrapped in fibrin network. Sticky bone graft doesn't scatter because particulate bone powders are strongly interconnected each other by fibrin network.
Interventional
N/A
分配:
干预模型: Single Group Assignment
干预模型描述:
盲法: Interventional
盲法描述:
主要目的: Treatment
  • Device: Ridge augmentation with sticky bone and GBR
    Autogenous particulate bone will be harvested and a mixture of autogenous particulate and anorganic bovine bone mineral will be prepared at a ratio of 1:1 Venous blood will be drawn from patients' forearm and centrifuged at 2500 RPM/3 minutes and 4000 RPM/15 minutes to produce autologous fibrin glue and concentrated growth factors membrane, respectively Sticky bone will be prepared by adding autologous fibrin glue to the particulate mixture, placed onto the defect and covered by the prepared concentrated growth factors membrane For guided bone regeneration the particulate mixture will be placed onto the defect and covered by resorbable collagen membrane Periosteal releasing incision will be done to provide flap advancement for tension free closure Closure will be done using horizontal mattress and interrupted 4/0 polypropylene sutures
  • Experimental: Ridge augmentation with sticky bone and GBR
    Ridge augmentation using Autologous concentrated Growth factors (CGF) enriched bone graft matrix (sticky bone) and guided bone regeneration using native collagen membrane in horizontally deficient maxilla
 
Not yet recruiting
24
与当前相同
October 20, 2019
September 20, 2019   (主要结果测量的最终数据收集日期)
Inclusion Criteria: - Inadequate facial bone obviating prosthodontically planned implant placement in the maxilla - Both sexes. - No intraoral soft and hard tissue pathology - No systemic condition that contraindicate implant placement. Exclusion Criteria: - Significant bone-related illness or pathology. - Heavy smokers more than 20 cigarettes per day. - Patients with systemic disease that may affect normal healing. - Psychiatric problems - Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site - Immunodeficiency pathology, bruxism, stress situation (socially or professionally).
参与研究的性别: All
最小年龄:20 Years ,最大年龄:60 Years  
没有
 
Yes
研究美国FDA监管的药品: No
研究涉及美国FDA监管的设备产品: No
计划分享 IPD:
Sarah AbdAllah Mohamed,Cairo University
Cairo University
:
Cairo University
October 2018

ICMJE     国际医学期刊编辑委员会和 世界卫生组织 ICTRP 要求的元素
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