Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR
赞助:
Cairo University
合作者:
信息的提供 (责任方):
Sarah AbdAllah Mohamed,Cairo University
追踪信息 | |||
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首次提交日期 ICMJE | October 4, 2018 | ||
首次发布日期e ICMJE | October 5, 2018 | ||
最后更新发布日期 | October 5, 2018 | ||
预计研究开始日期 ICMJE | October 20, 2018 | ||
预计主要完成日期 | September 20, 2019 (主要结果测量的最终数据收集日期) | ||
目前主要观察指标 ICMJE |
Horizontal bone gain[ Time Frame: 6 months ] The amount of horizontal bone gain will be measured by cone beam computed tomography |
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原始主要观察测量 ICMJE | 与当前相同 | ||
目前的二级观察 ICMJE |
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描述性信息 | |||
简略标题 ICMJE | Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR | ||
正式标题 ICMJE | Ridge Augmentation Using Autologous Concentrated Growth Factors (CGF) Enriched Bone Graft Matrix (Sticky Bone) Versus Guided Bone Regeneration Using Native Collagen Membrane in Horizontally Deficient Maxilla | ||
简要概况 | Guided bone regeneration (GBR) using bone graft and barrier membrane is a well-established technique for augmentation of atrophic alveolar ridges. There are many techniques for ridge augmentation involves the use of bone grafting materials, barrier membranes, possibly some tenting/fixation screws the stability of bone graft, space maintenance, angiogenesis, and tension free primary suture are essential for success. |
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详细说明 | Common techniques introduced for horizontal ridge augmentation are Guided Bone Regeneration (GBR), there are many techniques for ridge augmentation involves the use of bone grafting materials, barrier membranes, possibly some tenting/fixation screws. For successful GBR, stability of bone graft, space maintenance, angiogenesis, and tension free primary suture are essential. Space maintenance with particulate bone graft should be provided during healing period. However particulate bone graft is easily migrated when grafted on the large horizontal bone defect. To reconstruct large bony defect or for the 3-dimensional ridge augmentation, bone tack on the collagen membrane or titanium mesh is required to contain particulate bone graft during healing but these procedures are surgically time consuming and technique sensitive. Sticky bone is biologically solidified bone graft which is entrapped in fibrin network. Sticky bone graft doesn't scatter because particulate bone powders are strongly interconnected each other by fibrin network. | ||
研究类型 ICMJE | Interventional | ||
研究阶段 | N/A | ||
研究设计 ICMJE | 分配: 干预模型: Single Group Assignment 干预模型描述: 盲法: Interventional 盲法描述: 主要目的: Treatment |
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适用条件 ICMJE | |||
干预项目 ICMJE |
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研究工具 |
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招募信息 | |||
招募状态 ICMJE | Not yet recruiting | ||
预计入组 ICMJE |
24 | ||
原始预计入组 ICMJE | 与当前相同 | ||
预计研究完成日期 | October 20, 2019 | ||
预计主要完成日期 | September 20, 2019 (主要结果测量的最终数据收集日期) | ||
合格标准 ICMJE | Inclusion Criteria: - Inadequate facial bone obviating prosthodontically planned implant placement in the maxilla - Both sexes. - No intraoral soft and hard tissue pathology - No systemic condition that contraindicate implant placement. Exclusion Criteria: - Significant bone-related illness or pathology. - Heavy smokers more than 20 cigarettes per day. - Patients with systemic disease that may affect normal healing. - Psychiatric problems - Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site - Immunodeficiency pathology, bruxism, stress situation (socially or professionally). | ||
性别 |
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年龄 | 最小年龄:20 Years ,最大年龄:60 Years | ||
接受健康的志愿者 | 没有 | ||
可入组国家 ICMJE | |||
管理信息 | 数据检测委员会 | Yes | |
研究涉及美国FDA监管的产品 |
研究美国FDA监管的药品: No 研究涉及美国FDA监管的设备产品: No |
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IPD 共享声明 |
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责任方 | Sarah AbdAllah Mohamed,Cairo University | ||
研究赞助商 ICMJE | Cairo University | ||
合作者 ICMJE | |||
研究员 ICMJE |
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PRS 账户 | Cairo University | ||
验证日期 | October 2018 | ||
ICMJE 国际医学期刊编辑委员会和 世界卫生组织 ICTRP 要求的元素 |
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