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Selective Tibial Nerve Block vs Local Infiltration Analgesia After Prothetic Knee Surgery

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合作者:
信息的提供 (责任方):
Eric Albrecht,Centre Hospitalier Universitaire Vaudois
October 2, 2018
October 5, 2018
October 5, 2018
November 1, 2018
November 1, 2020   (主要结果测量的最终数据收集日期)
Total morphine consumption (mg)[ Time Frame: 24 hours postoperatively ]

与当前相同
  • Total morphine consumption (mg)[ Time Frame: 2 hours, 48 hours and 72 hours postoperatively ]
  • Analgesic duration (minutes)[ Time Frame: Postoperative day 0 ]
    Time from the block to the first analgesic request
  • Pain scores (numeric rating scale, 0-10) at rest and on movement[ Time Frame: 2 hours, 24 hours, 48 hours and 72 hours postoperatively ]
    0= no pain, 10=the worst pain imaginable
  • Rate of postoperative nausea and vomiting[ Time Frame: 2 hours, 24 hours, 48 hours and 72 hours postoperatively ]
    Yes/No
  • Rate of prurit[ Time Frame: 2 hours, 24 hours, 48 hours and 72 hours postoperatively ]
    Yes/No
  • Active flexion[ Time Frame: 24hours, 48hours and 72hours postoperatively ]
    Flexion of the knee by the patient measured in degrees
  • Passive flexion[ Time Frame: 24hours, 48hours and 72hours postoperatively ]
    Flexion of the knee by physiotherapist measured in degrees
  • Quadriceps muscle strength (numeric scale, 1-5)[ Time Frame: 24hours, 48hours and 72hours postoperatively ]
    1=no contraction, 5=normal strength
  • Distance walked (meters)[ Time Frame: 24hours, 48hours and 72hours postoperatively ]
  • Complication of the femoral or tibial nerve block[ Time Frame: up to 1 week ]
    Intravascular injection/hematoma/infection/Common peroneal nerve block
  • Length of stay in hospital[ Time Frame: up to 14 days ]
    Days
 
Selective Tibial Nerve Block vs Local Infiltration Analgesia After Prothetic Knee Surgery
Optimal Pain Control After Prothetic Knee Surgery Either by Selective Tibial Nerve Block Versus Local Infiltration Analgesia

Patient suffer from moderate posterior knee pain after TKA despite injection of local anesthetic around the femoral nerve (femoral nerve block). Indeed, the posterior part of the knee is innervated by the sciatic nerve. This nerve is not routinely blocked as clinicians fear to produce a motor block of the leg that might impair the postoperative assessment. An analgesic alternative is the infiltration of the knee with local anesthetics performed by the surgeon. Recently a trial(1) demonstrated that a selective tibial nerve block provides an effective analgesia without a motor blockage when compared with a sciatic nerve block. The objective of this randomized controlled double-blinded trial is to assess whether a tibial nerve block is more effective for the postoperative pain than local infiltration analgesia when there are combined with a femoral nerve block, without decreasing the functional parameters.

Interventional
N/A
分配: Randomized
干预模型: Parallel Assignment
干预模型描述:
盲法: Interventional
盲法描述:
主要目的: Treatment
  • Drug: Ropivacaine 0.5% Injectable Solution
    Tibial nerve block with 10ml of Ropivacaine 0.5%
  • Drug: Ropivacaine 0.2% Injectable Solution
    Infiltration with 25ml of Ropivacaine 0.2% in the posterior knee capsule
  • Experimental: Tibial nerve block
    Femoral nerve and tibial nerve blocks performed by the anesthetist under ultrasound guidance before spinal block.
  • Active Comparator: Local infiltration analgesia
    Femoral nerve block by the anesthetist under ultrasound guidance before spinal block. Infiltration of the knee by the surgeon with local anesthetic at the end of the surgery.
 
Not yet recruiting
60
与当前相同
November 1, 2021
November 1, 2020   (主要结果测量的最终数据收集日期)
Inclusion Criteria: - Patient scheduled for a total knee arthroplasty under spinal block. - Patient with a weight above 40kg. Exclusion Criteria: - Patient with ASA IV status. - Contraindication to spinal block, femoral nerve block or tibial nerve block. - Neurological deficit of the lower limb. - Patient with renal dysfunction. - Patient with chronic pain, opioid consumption or alcohol consumption. - Pregnancy.
参与研究的性别: All
最小年龄:18 Years ,最大年龄:N/A  
没有
 
Yes
研究美国FDA监管的药品: No
研究涉及美国FDA监管的设备产品: No
计划分享 IPD: Undecided
Eric Albrecht,Centre Hospitalier Universitaire Vaudois
Centre Hospitalier Universitaire Vaudois
:
Centre Hospitalier Universitaire Vaudois
October 2018

ICMJE     国际医学期刊编辑委员会和 世界卫生组织 ICTRP 要求的元素
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