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这是一项关于Medulloblastoma Recurrent的II 期研究，登记的药物或干预包括Bevacizumab；Thalidomide；Celecoxib；Fenofibric acid；Etoposide；Cyclophosphamide；Cytarabine；Temozolomide (TMZ)；Irinotecan，当前状态为招募中。登记地点显示中国Chicago、Boston、Grand Rapids、Austin等城市有研究中心记录。是否仍有名额以及是否值得进一步询问，需要向研究中心确认。
药物或干预
Bevacizumab；Thalidomide；Celecoxib；Fenofibric acid；Etoposide；Cyclophosphamide；Cytarabine；Temozolomide (TMZ)；Irinotecan · II 期
中国哪些地方有记录
以下地点来自登记信息，不代表此刻仍有名额；请向研究中心确认最新情况。
- Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago
- Dana-Farber Cancer Institute and Boston Children's Hospital · Boston
- Helen DeVos Children's Hospital · Grand Rapids
- Dell Children's Medical Group SFC-HEM/ONC · Austin
- Medical University of Graz · Graz
- Medical University of Innsbruck · Innsbruck
- Kepler Universitätsklinikum Med Campus IV · Linz
- Salzburger Universitätsklinikum · Salzburg
- Medical University of Vienna · Vienna
- University Hospital Brno · Brno
- Motol University Hospital Prague · Prague
- University hospital Rigshospitalet · Copenhagen
- Centre Oscar Lambret · Lille
- Centre Léon Bérard · Lyon
- Onkologisk-hematologisk seksjon Barneklinikken Haukeland universitetssjukehus · Bergen
- Hospital Infantil Universitario Nino Jesus · Madrid
- Sahlgrenska Universitetssjukhuset · Gothenburg
- Universitetssjukhuset Linköping · Linköping
- Skånes universitetssjukhus · Lund
- Karolinska University Hospital · Stockholm
- Norrlands Universitetssjukhus · Umeå
- Akademiska sjukhuset · Uppsala
公开的入选条件
- Inclusion criteria for patients
- * Stratum I: Relapsed or progressive medulloblastoma
- completed
- * Stratum II: Relapsed or progressive ependymoma (at least one site of untreated recurrent disease)
- * Stratum III: Relapsed or progressive ATRT (at least one site of untreated recurrent disease)
- * Stratum IV: Relapsed or progressive medulloblastoma (at least one site of untreated recurrent disease)
- * Stratum V: Relapsed or progressive CNS tumor of various histologies or patients with exclusion criteria or adult patients (explorative)
- * Histological confirmation at diagnosis or relapse Stratum IV: Confirmation of the medulloblastoma group by methylation; IDAT (Intensity Data; raw data of methylation array)
联系前需要确认
请继续确认中心是否启动、疾病分型、既往治疗、检查费用和知情同意安排。
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登记号：NCT01356290；登记信息更新于 2026-09-10。