研究项目库 / NCT07431827

Calderasib用于非小细胞肺癌的III 期研究

这是一项关于非小细胞肺癌的III 期研究,登记的药物或干预包括Calderasib;MK-3475A;Placebo,当前状态为招募中。登记地点显示中国北京、重庆、福州、广州等城市有研究中心记录。是否仍有名额以及是否值得进一步询问,需要向研究中心确认。

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这是一项关于非小细胞肺癌的III 期研究,登记的药物或干预包括Calderasib;MK-3475A;Placebo,当前状态为招募中。登记地点显示中国北京、重庆、福州、广州等城市有研究中心记录。是否仍有名额以及是否值得进一步询问,需要向研究中心确认。

药物或干预

Calderasib;MK-3475A;Placebo · III 期

中国哪些地方有记录

以下地点来自登记信息,不代表此刻仍有名额;请向研究中心确认最新情况。

  • Peking University People's Hospital ( Site 2100) · 北京
  • Beijing Cancer hospital ( Site 2106) · 北京
  • Peking Union Medical College Hospital ( Site 2105) · 北京
  • Chongqing University Three Gorges Hospital ( Site 2138) · 重庆
  • The First Affiliated Hospital Of Fujian Medical University ( Site 2123) · 福州
  • Fujian Cancer Hospital ( Site 2122) · 福州
  • Sun Yat-sen University Cancer Center ( Site 2134) · 广州
  • Guangxi Medical University Cancer Hospital ( Site 2115) · 南宁
  • Fourth Hospital Of Hebei Medical University ( Site 2107) · 石家庄
  • Tongji Hospital Tongji Medical,Science & Technology ( Site 2140) · 武汉
  • Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 2139) · 武汉
  • Xiangya Hospital Central South University ( Site 2136) · 长沙
  • The First Affiliated Hospital of Nanchang University ( Site 2121) · 南昌
  • Shanghai Pulmonary Hospital ( Site 2125) · 上海
  • Fudan University Shanghai Cancer Center ( Site 2137) · 上海
  • Zhongshan Hospital of Fudan University ( Site 2119) · 上海
  • West China Hospital, Sichuan University ( Site 2142) · 成都
  • The Third Peoples Hospital Of Chengdu ( Site 2141) · 成都
  • Sichuan Cancer hospital ( Site 2101) · 成都
  • The Affiliated Cancer Hospital of Xinjiang Medical ( Site 2110) · 乌鲁木齐
  • Yunnan Province Cancer Hospital ( Site 2131) · 昆明
  • Sir Run Run Shaw Hospital of Zhejiang University School of Medicine ( Site 2118) · 杭州
  • The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 2103) · 杭州
  • Zhejiang Cancer Hospital ( Site 2117) · 杭州
  • Ningbo No. 2 Hospital ( Site 2124) · 宁波

公开的入选条件

  • * Has a histological/cytological diagnosis of non-small cell lung cancer (NSCLC) with predominantly nonsquamous histology and meets one of the following criteria:
  • Has newly diagnosed, treatment-naïve, resectable, clinical Stage IIA-IIIB (N2) NSCLC
  • Has completely resected, pathological Stage IIA-IIIB (N2) NSCLC, including those previously treated outside the study with neoadjuvant platinum-doublet chemotherapy plus pembrolizumab or MK-3475A, or those who received adjuvant platinum-doublet chemotherapy.
  • * Tumor tissue shows the presence of Kirsten rat sarcoma viral oncogene homolog G12C (KRAS G12C) mutation
  • * No more than 12 weeks have elapsed between either the surgery following neoadjuvant treatment or last dose of adjuvant platinum-based chemotherapy and the first dose of investigational adjuvant study intervention.
  • * Has no evidence of disease based on postsurgical radiological assessment as documented by contrast-enhanced chest/abdomen computed tomography (or magnetic resonance imaging) within 28 days before randomization
  • * Has an Eastern Cooperative Oncology Group performance status of 0 or 1 within 10 days before the first dose of the study intervention
  • * Human immunodeficiency virus-infected participants must have well controlled HIV on antiretroviral therapy

联系前需要确认

请继续确认中心是否启动、疾病分型、既往治疗、检查费用和知情同意安排。

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登记号:NCT07431827;登记信息更新于 2026-09-14。

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