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这是一项关于结直肠癌的II 期研究，登记的药物或干预包括VVD-133214；Pembrolizumab，当前状态为招募中。登记地点显示中国蚌埠、北京、福州、广州等城市有研究中心记录。是否仍有名额以及是否值得进一步询问，需要向研究中心确认。
药物或干预
VVD-133214；Pembrolizumab · II 期
中国哪些地方有记录
以下地点来自登记信息，不代表此刻仍有名额；请向研究中心确认最新情况。
- The First Affiliated Hospital of Bengbu Medical College · 蚌埠
- Beijing Cancer Hospital - Oncology Department · 北京
- Fujian Cancer Hospital · 福州
- The Sixth Affiliated Hospital, Sun Yat-sen University · 广州
- Harbin Medical University Cancer Hospital · 哈尔滨
- Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology · 武汉
- Shandong University - Shandong Cancer Hospital · 济南
- Zhongshan Hospital, Fudan University · 上海
- West China Hospital Sichuan University · 成都
- Yunnan Cancer Hospital · 昆明
- Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine - Oncology Department · 杭州
- Zhejiang Cancer Hospital · 杭州
公开的入选条件
- * Eastern Cooperative Oncology Group (ECOG) performance-status score of 0 or 1
- * Have a known microsatellite instability (MSI) and/or deficient mismatch repair (dMMR) tumor status confirmed per local standard of care (SoC), and have histologically or cytologically documented advanced (unresectable and/or metastatic) colorectal adenocarci
- * No prior systemic treatment for metastatic disease and not amenable to curative resection
- * Participants must have documented MSI and/or dMMR tumor status determined as part of the routine diagnostic workup in a certified laboratory
- * Availability of formaldehyde-fixed paraffin-embedded (FFPE) archival tumor tissue for submission to Sponsor/central laboratory for retrospective central testing including a copy of a redacted pathology report if available
- * Presence of measurable disease according to RECIST v1.1
- * Adequate hematologic and end-organ function, defined using laboratory results obtained within 14 days prior to first dose of study treatment
- * Females of childbearing potential must have negative serum pregnancy test before starting study treatment
联系前需要确认
请继续确认中心是否启动、疾病分型、既往治疗、检查费用和知情同意安排。
查看登记信息
登记号：NCT07811193；登记信息更新于 2026-09-16。